Coverage: Live on BBC Two, BBC Sport website, BBC Radio 5 live, BBC local radio & highlights on The Football League Show
Burnley will be without first-choice right-back and former Preston player Tyrone Mears through suspension.Striker Chris Iwelumo looks set to play after a hamstring problem, with Michael Duff also returning to the squad.
Preston boss Darren Ferguson hopes to pick from a full-strength squad after Keith Treacy's groin injury cleared up.
Craig Morgan has shaken off a toe problem, while new signing Wayne Brown has finally overcoming a torn calf that has delayed his North End debut.
MATCH PREVIEWBurnley host near-neighbours Preston for the first time since suffering relegation from the Premier League. They are the only two Lancastrian sides in this season's Championship so a victory will taste all the more sweeter for either club and their fans.
The Clarets suffered their first defeat of the campaign at Swansea last time out but have won eight straight home games at this level. Manager Brian Laws knows his side need to keep that run going to remain among the pacesetters of the fledgling Championship table.
Preston are the longest serving members of England's second tier but have made a slow start to their 11th straight campaign in this division. Darren Ferguson's men have scored just once in 360 league minutes, but four wins in their last five games against Burnley will give them renewed hope.
For added spice, the Clarets could field recent Preston recruit Ross Wallace and Lilywhites legend Graham Alexander in their side. However, Tyrone Mears is suspended. North End could field ex-Burnley Academy graduate Richard Chaplow.
• This will be the 123rd league meeting between these two sides, Preston have won 51 games, Burnley 45, with 26 drawn.
• Preston have won four of their last five encounters against Burnley.
• Fourteen goals have been scored in the last three league meetings at Turf Moor: Burnley won 3-1 (Sep 2008) and 3-2 (Oct 2006). Preston won 3-2 (Dec 2007).
• The Clarets have won six of their last 10 home encounters against Preston.
• The last team to win at Turf Moor at Championship level was Sheffield Wednesday, who won 4-2 in February 2009. Incidentally they were managed by current Burnley boss Brian Laws.
• If selected, Brian Jensen will be making his 250th Clarets appearance, while Chris Eagles is on the verge of his 100th career game.
• Preston have lost 10 of their last 11 away Championship matches (including two this season). Their only away win under boss Darren Ferguson came against his former club Peterborough last January.
• North End have failed to score in three of their four league games - as have Portsmouth.
• Paul Hayes stands by to make his 300th club career start.